Personally, of all the things you can Smoke or BBQ (Or whatever region you're from calls it) Brisket is the king of beef.
Someone on these forums once said (many times) "Even bad BBQ can make awesome chili" and I'm a true believer in that. Things someone personally thinks they messed up, give them 24 hours and suddenly they have some of the most delicious looking soups, stews, chilis or hashes I've ever seen.
I love brisket, it's corned beef, it's pastrami, it's burnt ends... it's everything I love about cooking, so versatile and so tasty, the sky is the limit.
The true history of BBQ is about taking the scraps or throwaway portions of the animal that the wealthy didn't want, and turning it into food for your family. We've turned what was trash into a highly sought after cut of meat with culinary know how and creative cooking, same thing happened to Lobster..
I've got a 12.4lb brisket going in the smoker Monday, can not wait to fire it up and taste the results...