Certainly can
I like to rub my beef ribs the night before with salt, pepper, garlic powder, onion powder and some chili powder. You don't have to do it over night, it just only makes the flavors better..l put them on the smoker for 2 hours at 275. Remove and place them in foil with some beef broth, wrap them up tight and put them back on the smoker for 2 more hours. Sauce them lightly with something sweet, I tend to like a vinegar sauce with some fruit jelly, apple jelly has been my new thing lately. Put them back on for 10-15 min to let your sauce caramelize then let rest for 10 min or so before you slice, then pig out!