Layer...savory then sweet...:thumb:
I like layering because I can adjust each from cook off to cook off, Texas is really big! Different areas of Texas like different bbq, maybe not way different but at least a little. Also allows to leave something out completely if you think it will help at that particular event, like the heat and or sweets, salt ect.
Here was a really good discussion on this, including some insight from some rub makers.
http://www.bbq-brethren.com/forum/showthread.php?t=217607