I use ground turkey meat all the time for fatty's - lots of health conscious friends and family. I have 3 of them I am about to smoke in an hour or so. I add 1 egg and some bread crumbs to the turkey meat, mix it all up, then make the fattys. I find the egg/bread crumbs help to bind the meat. I also make 'em a day in advance so they can form and hold their shape.
I stuff 'em with anything, but never thought to do a thanksgiving one - I like that idea!